Metabotropic Glutamate Receptor 1 抗体 (C-Term)
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- 抗原 See all Metabotropic Glutamate Receptor 1 (GRM1) 抗体
- Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))
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抗原表位
- C-Term
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Metabotropic Glutamate Receptor 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 交叉反应
- 小鼠, 大鼠
- 交叉反应 (详细)
- Cross reactivity from other sources has not been determined.
- 纯化方法
- Anti-mGluR1a antibodies are affinity purified from monospecific antiserum by immunoaffinity purification. Immunolabeling blocked by preadsorption of antibody with the peptide used to generate the antibody. This antibody is directed against rat mGluR1a. Reactivity is expected from mouse.
- 免疫原
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Immunogen: Anti-mGluR1a Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
Immunogen Type: Peptide
- 亚型
- IgG
- Top Product
- Discover our top product GRM1 Primary Antibody
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- 应用备注
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Immunohistochemistry Dilution: 1:500
Application Note: Anti-mGluR1a antibody is suitable for use in Western Blotting and IHC. Expect a band of approximately 125 kDa monomer and 250 kDa mGluR1a dimer in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.
Western Blot Dilution: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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- 抗原
- Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))
- 别名
- mGluR1a (GRM1 产品)
- 别名
- fj39d05 antibody, wu:fj39d05 antibody, si:ch211-51a19.1 antibody, Glura antibody, mGlutR antibody, GB18621 antibody, GPRC1A antibody, MGLU1 antibody, MGLUR1 antibody, SCAR13 antibody, 4930455H15Rik antibody, ENSMUSG00000075319 antibody, Gm10828 antibody, Gprc1a antibody, mGluR1 antibody, nmf373 antibody, rcw antibody, wobl antibody, glutamate metabotropic receptor 1 antibody, glutamate receptor, metabotropic 1a antibody, metabotropic glutamate receptor 1 antibody, glutamate receptor, metabotropic 1 antibody, GRM1 antibody, grm1a antibody, mGlutR1 antibody, Grm1 antibody
- 背景
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Synonyms: mGluR1, Metabotropic Glutamate Receptor 1a
Background: mGluR1a antibodies detect GluR1a. GluR1a is the metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse. Group I metabotropic glutamate receptors (consisting of mGluR1 and mGluR5) are G-protein-coupled neurotransmitter receptors that are localized in the perisynaptic region of the postsynaptic membrane. When activated, Group I mGluRs lead to stimulation of phospholipase and activation of Protein Kinase C. In contrast, activation of Group II metabotropic receptors (mGluR2 and mGluR3) leads to inhibition of adenylate cyclase. The mGluR1 receptor may also be critically involved in limiting the deleterious effects of excitotoxicity. Therefore, mGluR1a antibody is ideal for investigators involved in neuronal plasticitiy, cell signaling and neuroscience.
Gene Name: GRM1
- 基因ID
- 24414
- UniProt
- P23385
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