FZD8 抗体 (AA 486-535)
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北京 101111
Quick Overview for FZD8 抗体 (AA 486-535) (ABIN1535685)
抗原
See all FZD8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 486-535
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原理
- Frizzled-8 Antibody
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特异性
- Frizzled-8 Polyclonal Antibody detects endogenous levels of Frizzled-8 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human FZD8. AA range:486-535
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- FZD8 (Frizzled Family Receptor 8 (FZD8))
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别名
- FZD8
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背景
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Synonyms: FZD8, Frizzled-8, Fz-8, hFz8
Background: frizzled class receptor 8(FZD8) Homo sapiens This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008],
Gene Name: FZD8
Protein Name: Frizzled-8
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分子量
- 73 kDa
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基因ID
- 8325
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OMIM
- 606146
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UniProt
- Q9H461
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途径
- WNT signaling
抗原
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