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FZD8 抗体 (AA 486-535)

This 兔 多克隆 antibody specifically detects FZD8 in WB, ELISA, IHC 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1535685
发货至: 中国
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Quick Overview for FZD8 抗体 (AA 486-535) (ABIN1535685)

抗原

See all FZD8 抗体
FZD8 (Frizzled Family Receptor 8 (FZD8))

适用

  • 69
  • 40
  • 28
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 66
  • 3
  • 2
  • 2
兔

克隆类型

  • 53
  • 20
多克隆

标记

  • 30
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FZD8 antibody is un-conjugated

应用范围

  • 47
  • 24
  • 15
  • 12
  • 10
  • 7
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 486-535

    原理

    Frizzled-8 Antibody

    特异性

    Frizzled-8 Polyclonal Antibody detects endogenous levels of Frizzled-8 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human FZD8. AA range:486-535

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    FZD8 (Frizzled Family Receptor 8 (FZD8))

    别名

    FZD8

    背景

    Synonyms: FZD8, Frizzled-8, Fz-8, hFz8

    Background: frizzled class receptor 8(FZD8) Homo sapiens This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008],

    Gene Name: FZD8

    Protein Name: Frizzled-8

    分子量

    73 kDa

    基因ID

    8325

    OMIM

    606146

    UniProt

    Q9H461

    途径

    WNT signaling
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