BDKRB1 抗体 (AA 201-250)
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北京 101111
Quick Overview for BDKRB1 抗体 (AA 201-250) (ABIN1535653)
抗原
See all BDKRB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-250
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原理
- Bradykinin B1 R Antibody
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特异性
- Bradykinin B1 R Polyclonal Antibody detects endogenous levels of Bradykinin B1 R protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human BDKRB1. AA range:201-250
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- BDKRB1 (Bradykinin Receptor B1 (BDKRB1))
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别名
- BDKRB1
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背景
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Synonyms: BDKRB1, BRADYB1, B1 bradykinin receptor, B1R, BK-1 receptor
Background: Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions.The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
Gene Name: BDKRB1
Protein Name: B1 bradykinin receptor
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分子量
- 40 kDa
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基因ID
- 623
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OMIM
- 600337
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UniProt
- P46663
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途径
- ACE Inhibitor Pathway
抗原
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