FZD7 抗体 (AA 45-94)
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北京 101111
Quick Overview for FZD7 抗体 (AA 45-94) (ABIN1535614)
抗原
See all FZD7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 45-94
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原理
- Frizzled-7 Antibody
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特异性
- Frizzled-7 Polyclonal Antibody detects endogenous levels of Frizzled-7 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human FZD7. AA range:45-94
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亚型
- IgG
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应用备注
- WB 1:500-2000,Flow Cyt 1:50-200,IF ICC 1:100-500,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- FZD7 (Frizzled Family Receptor 7 (FZD7))
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别名
- FZD7
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背景
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Synonyms: FZD7; Frizzled-7; Fz-7; hFz7; FzE3
Background: frizzled class receptor 7(FZD7) Homo sapiens Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008],
Gene Name: FZD7
Protein Name: Frizzled-7
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分子量
- 63 kDa
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基因ID
- 8324
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OMIM
- 603410
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UniProt
- O75084
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途径
- WNT signaling, Stem Cell Maintenance
抗原
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