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FZD7 抗体 (AA 45-94)

The 兔 多克隆 anti-FZD7 antibody is suitable to detect FZD7 in samples from 人 和 小鼠. It has been validated for WB, ELISA, FACS 和 IF.
产品编号 ABIN1535614
发货至: 中国
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Quick Overview for FZD7 抗体 (AA 45-94) (ABIN1535614)

抗原

See all FZD7 抗体
FZD7 (Frizzled Family Receptor 7 (FZD7))

适用

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人, 小鼠

宿主

  • 48
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兔

克隆类型

  • 51
  • 9
多克隆

标记

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This FZD7 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)
  • 抗原表位

    • 16
    • 9
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    • 1
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    AA 45-94

    原理

    Frizzled-7 Antibody

    特异性

    Frizzled-7 Polyclonal Antibody detects endogenous levels of Frizzled-7 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human FZD7. AA range:45-94

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,Flow Cyt 1:50-200,IF ICC 1:100-500,ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    FZD7 (Frizzled Family Receptor 7 (FZD7))

    别名

    FZD7

    背景

    Synonyms: FZD7; Frizzled-7; Fz-7; hFz7; FzE3

    Background: frizzled class receptor 7(FZD7) Homo sapiens Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008],

    Gene Name: FZD7

    Protein Name: Frizzled-7

    分子量

    63 kDa

    基因ID

    8324

    OMIM

    603410

    UniProt

    O75084

    途径

    WNT signaling, Stem Cell Maintenance
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