CBP 抗体 (AA 1501-1550)
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北京 101111
Quick Overview for CBP 抗体 (AA 1501-1550) (ABIN1535551)
抗原
See all CBP (CREBBP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1501-1550
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原理
- CREB-BP Antibody
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特异性
- CBP Polyclonal Antibody detects endogenous levels of CBP protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CBP. AA range:1501-1550
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CBP (CREBBP) (CREB Binding Protein (CREBBP))
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别名
- CBP
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背景
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Synonyms: CREBBP, CBP, CREB-binding protein
Background: This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition.The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations invo
Gene Name: CREBBP
Protein Name: CREB-binding protein
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分子量
- 265 kDa
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基因ID
- 1387
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OMIM
- 600140
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UniProt
- Q92793
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途径
- TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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