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Renin 抗体 (AA 207-256)

The 兔 多克隆 anti-Renin antibody (ABIN485907) specifically detects Renin in WB, IHC, ELISA 和 IF. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN485907
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Renin 抗体 (AA 207-256) (ABIN485907)

抗原

See all Renin (REN) 抗体
Renin (REN)

适用

  • 104
  • 48
  • 33
  • 2
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  • 1
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人, 大鼠, 小鼠

宿主

  • 105
  • 19
  • 17
  • 2
  • 2
兔

克隆类型

  • 114
  • 30
多克隆

标记

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  • 1
  • 1
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This Renin antibody is un-conjugated

应用范围

  • 96
  • 48
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  • 31
  • 13
  • 13
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  • 11
  • 8
  • 5
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 15
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    • 13
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 207-256

    原理

    Renin Antibody

    特异性

    Renin Polyclonal Antibody detects endogenous levels of Renin protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human REN. AA range:207-256

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Renin (REN)

    别名

    REN

    背景

    Synonyms: REN, Renin, Angiotensinogenase

    Background: Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008],

    Gene Name: REN

    Protein Name: Renin

    分子量

    45 kDa

    基因ID

    5972

    OMIM

    179820

    UniProt

    P00797

    途径

    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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