GFR 抗体 (AA 431-480)
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Quick Overview for GFR 抗体 (AA 431-480) (ABIN1535258)
抗原
See all GFR (RAPGEF5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 431-480
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原理
- Repac Antibody
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特异性
- Repac Polyclonal Antibody detects endogenous levels of Repac protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human RAPGEF5. AA range:431-480
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GFR (RAPGEF5) (Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5))
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别名
- RAPGEF5
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背景
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Synonyms: RAPGEF5, GFR, KIAA0277, MRGEF, Rap guanine nucleotide exchange factor 5, Guanine nucleotide exchange factor for Rap1, M-Ras-regulated Rap GEF, MR-GEF, Related to Epac, Repac
Background: Members of the RAS (see HRAS, MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008],
Gene Name: RAPGEF5
Protein Name: Rap guanine nucleotide exchange factor 5
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分子量
- 67 kDa
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基因ID
- 9771
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OMIM
- 609527
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UniProt
- Q92565
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途径
- RTK signaling, Neurotrophin Signaling Pathway, Hepatitis C
抗原
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