PMS2 抗体 (AA 125-174)
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Quick Overview for PMS2 抗体 (AA 125-174) (ABIN1535227)
抗原
See all PMS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 125-174
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原理
- PMS2/PMS2CL Antibody
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特异性
- PMS2/PMS2CL Polyclonal Antibody detects endogenous levels of PMS2/PMS2CL protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PMS2CL. AA range:125-174
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PMS2 (PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))
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别名
- PMS2/PMS2CL
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背景
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Synonyms: PMS2CL, Protein PMS2CL, PMS2-C terminal-like protein, PMS2, PMSL2, Mismatch repair endonuclease PMS2, DNA mismatch repair protein PMS2, PMS1 protein homolog 2
Background: caution:According to PubMed:15077197, it is a pseudogene. However, a peptide specific to this protein was identified by mass spectrometry (PubMed:17525332). Given that the product described by PubMed:15077197 is located downstream and on another frame of the transcript, it may explain why PubMed:15256438 could not detect this protein on a Western blot.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Wrong choice of transcript.,similarity:Belongs to the DNA mismatch repair mutL/hexB family.,
Gene Name: PMS2/PMS2CL
Protein Name: Mismatch repair endonuclease PMS2/Protein PMS2CL
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分子量
- 20 kDa
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基因ID
- 5395
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OMIM
- 276300
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UniProt
- Q68D20
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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