LAMP3 抗体 (AA 274-323)
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Quick Overview for LAMP3 抗体 (AA 274-323) (ABIN1535014)
抗原
See all LAMP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 274-323
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原理
- DC-LAMP Antibody
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特异性
- DC-LAMP Polyclonal Antibody detects endogenous levels of DC-LAMP protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human LAMP3. AA range:274-323
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亚型
- IgG
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应用备注
- Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- LAMP3 (Lysosomal-Associated Membrane Protein 3 (LAMP3))
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别名
- LAMP3
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背景
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Synonyms: LAMP3, DCLAMP, TSC403, Lysosome-associated membrane glycoprotein 3, LAMP-3, Lysosomal-associated membrane protein 3, DC-lysosome-associated membrane glycoprotein, DC LAMP, Protein TSC403, CD antigen CD208
Background: MET proto-oncogene, receptor tyrosine kinase(MET) Homo sapiens This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016],
Gene Name: LAMP3
Protein Name: Lysosome-associated membrane glycoprotein 3
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分子量
- 44 kDa
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OMIM
- 605883
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UniProt
- Q9UQV4
抗原
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