POLE 抗体 (AA 1261-1310)
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北京 101111
Quick Overview for POLE 抗体 (AA 1261-1310) (ABIN1534837)
抗原
See all POLE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1261-1310
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原理
- DNA pol ε A Antibody
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特异性
- DNA pol ε A Polyclonal Antibody detects endogenous levels of DNA pol ε A protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human POLE1. AA range:1261-1310
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- POLE (Polymerase (DNA Directed), Epsilon, Catalytic Subunit (POLE))
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别名
- POLE1
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背景
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Synonyms: POLE, POLE1, DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A
Background: DNA polymerase epsilon, catalytic subunit(POLE) Homo sapiens This gene encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in this gene have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature. [provided by RefSeq, Sep 2013],
Gene Name: POLE
Protein Name: DNA polymerase epsilon catalytic subunit A
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分子量
- 261 kDa
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基因ID
- 5426
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OMIM
- 174762
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UniProt
- Q07864
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途径
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
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