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CLDN8 抗体 (AA 81-130)

The 兔 多克隆 anti-CLDN8 antibody is suitable to detect CLDN8 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN1534783
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CLDN8 抗体 (AA 81-130) (ABIN1534783)

抗原

See all CLDN8 抗体
CLDN8 (Claudin 8 (CLDN8))

适用

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人, 小鼠, 大鼠

宿主

  • 27
  • 2
兔

克隆类型

  • 29
多克隆

标记

  • 17
  • 2
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This CLDN8 antibody is un-conjugated

应用范围

  • 20
  • 9
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Western Blotting (WB), ELISA
  • 抗原表位

    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 81-130

    原理

    Claudin-8 Antibody

    特异性

    Claudin-8 Polyclonal Antibody detects endogenous levels of Claudin-8 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human CLDN8. AA range:81-130

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    CLDN8 (Claudin 8 (CLDN8))

    别名

    CLDN8

    背景

    Synonyms: CLDN8, Claudin-8

    Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.[provided by RefSeq, May 2010],

    Gene Name: CLDN8

    Protein Name: Claudin-8

    分子量

    24 kDa

    基因ID

    9073

    OMIM

    611231

    UniProt

    P56748

    途径

    Hepatitis C
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