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CEP57 抗体 (AA 241-290)

The 兔 多克隆 anti-CEP57 antibody (ABIN1534754) specifically detects CEP57 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1534754
发货至: 中国
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Quick Overview for CEP57 抗体 (AA 241-290) (ABIN1534754)

抗原

See all CEP57 抗体
CEP57 (Centrosomal Protein 57kDa (CEP57))

适用

  • 45
  • 5
  • 4
  • 1
人, 小鼠, 大鼠

宿主

  • 41
  • 4
兔

克隆类型

  • 44
  • 1
多克隆

标记

  • 20
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CEP57 antibody is un-conjugated

应用范围

  • 21
  • 13
  • 13
  • 13
  • 6
  • 5
  • 5
  • 3
  • 2
  • 2
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 241-290

    原理

    CEP57 Antibody

    特异性

    CEP57 Polyclonal Antibody detects endogenous levels of CEP57 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human CEP57. AA range:241-290

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    CEP57 (Centrosomal Protein 57kDa (CEP57))

    别名

    CEP57

    背景

    Synonyms: CEP57, KIAA0092, TSP57, Centrosomal protein of 57 kDa, Cep57, FGF2-interacting protein, Testis-specific protein 57, Translokin

    Background: This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple

    Gene Name: CEP57

    Protein Name: Centrosomal protein of 57 kDa

    分子量

    57 kDa

    基因ID

    9702

    OMIM

    607951

    UniProt

    Q86XR8

    途径

    M Phase, Maintenance of Protein Location, Protein targeting to Nucleus, Growth Factor Binding
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