PMS1 抗体 (AA 441-490)
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北京 101111
Quick Overview for PMS1 抗体 (AA 441-490) (ABIN1534483)
抗原
See all PMS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 441-490
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原理
- PMS1 Antibody
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特异性
- PMS1 Polyclonal Antibody detects endogenous levels of PMS1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PMS1. AA range:441-490
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))
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别名
- PMS1
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背景
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Synonyms: PMS1, PMSL1, PMS1 protein homolog 1, DNA mismatch repair protein PMS1
Background: This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008],
Gene Name: PMS1
Protein Name: PMS1 protein homolog 1
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分子量
- 105 kDa
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基因ID
- 5378
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OMIM
- 600258
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UniProt
- P54277
抗原
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