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MSH6 抗体 (AA 341-390)

This 兔 多克隆 antibody specifically detects MSH6 in WB, IHC, IF 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 猴.
产品编号 ABIN1534473
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MSH6 抗体 (AA 341-390) (ABIN1534473)

抗原

See all MSH6 抗体
MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

适用

  • 229
  • 60
  • 52
  • 7
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 猴

宿主

  • 142
  • 84
  • 3
兔

克隆类型

  • 156
  • 72
  • 1
多克隆

标记

  • 126
  • 12
  • 5
  • 5
  • 5
  • 5
  • 5
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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
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This MSH6 antibody is un-conjugated

应用范围

  • 160
  • 118
  • 97
  • 57
  • 48
  • 47
  • 36
  • 32
  • 14
  • 14
  • 7
  • 4
  • 3
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
  • 抗原表位

    • 68
    • 15
    • 15
    • 14
    • 13
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 341-390

    原理

    GTBP Antibody

    特异性

    GTBP Polyclonal Antibody detects endogenous levels of GTBP protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human MSH6. AA range:341-390

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

    别名

    MSH6

    背景

    Synonyms: MSH6, GTBP, DNA mismatch repair protein Msh6, hMSH6, G/T mismatch-binding protein, GTBP, GTMBP, MutS-alpha 160 kDa subunit, p160

    Background: This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013],

    Gene Name: MSH6

    Protein Name: DNA mismatch repair protein Msh6

    分子量

    152 kDa

    基因ID

    2956

    OMIM

    600678

    UniProt

    P52701

    途径

    DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response
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