MSH3 抗体 (AA 51-100)
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北京 101111
Quick Overview for MSH3 抗体 (AA 51-100) (ABIN1534472)
抗原
See all MSH3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-100
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原理
- MSH3 Antibody
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特异性
- MSH3 Polyclonal Antibody detects endogenous levels of MSH3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MSH3. AA range:51-100
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MSH3 (MutS Homolog 3 (MSH3))
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别名
- MSH3
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背景
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Synonyms: MSH3, DUC1, DUG, DNA mismatch repair protein Msh3, hMSH3, Divergent upstream protein, DUP, Mismatch repair protein 1, MRP1
Background: The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011],
Gene Name: MSH3
Protein Name: DNA mismatch repair protein Msh3
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分子量
- 127 kDa
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基因ID
- 4437
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OMIM
- 600887
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UniProt
- P20585
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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