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MLH1 抗体 (AA 441-490)

The 兔 多克隆 anti-MLH1 antibody is suitable to detect MLH1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 IHC.
产品编号 ABIN1534468
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MLH1 抗体 (AA 441-490) (ABIN1534468)

抗原

See all MLH1 抗体
MLH1 (MutL Homolog 1 (MLH1))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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多克隆

标记

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This MLH1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 441-490

    原理

    MLH1 Antibody

    特异性

    MLH1 Polyclonal Antibody detects endogenous levels of MLH1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human MLH1. AA range:441-490

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MLH1 (MutL Homolog 1 (MLH1))

    别名

    MLH1

    背景

    Synonyms: MLH1, COCA2, DNA mismatch repair protein Mlh1, MutL protein homolog 1

    Background: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009],

    Gene Name: MLH1

    Protein Name: DNA mismatch repair protein Mlh1

    分子量

    84 kDa

    基因ID

    4292

    OMIM

    120436

    UniProt

    P40692

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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