ADCY5/6 抗体 (AA 931-980)
Our Local Distributor
北京 101111
Quick Overview for ADCY5/6 抗体 (AA 931-980) (ABIN1534255)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 931-980
-
原理
- A Cyclase V/VI Antibody
-
特异性
- A Cyclase V/VI Polyclonal Antibody detects endogenous levels of A Cyclase V/VI protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human ADCY5/6. AA range:931-980
-
亚型
- IgG
-
-
-
-
应用备注
- IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- ADCY5/6 (Adenylate Cyclase 5/6 (ADCY5/6))
-
背景
-
Synonyms: ADCY6, KIAA0422, Adenylate cyclase type 6, ATP pyrophosphate-lyase 6, Adenylate cyclase type VI, Adenylyl cyclase 6, Ca(2+)-inhibitable adenylyl cyclase, ADCY5, Adenylate cyclase type 5, ATP pyrophosphate-lyase 5, Adenylate cyclase type V,
Background: This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic loop, and a C-terminal cytoplasmic domain. The two cytoplasmic regions bind ATP and form the catalytic core of the protein. Adenylyl cyclases are important effectors of transmembrane signaling pathways and are regulated by the activity of G protein coupled receptor signaling. This protein belongs to a small subclass of adenylyl cyclase proteins that are functionally related and are inhibited by protein kinase A, calcium ions and nitric oxide. A mutation in this gene is associated with arthrogryposis multiplex congenita. [provided by RefSeq, May 2015],
Gene Name: ADCY5/ADCY6
Protein Name: Adenylate cyclase type 5/6
-
分子量
- 130 kDa
-
基因ID
- 112, 111
-
OMIM
- 600294
-
UniProt
- O43306
抗原
-