ADCY5/6 抗体 (AA 931-980)
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北京 101111
Quick Overview for ADCY5/6 抗体 (AA 931-980) (ABIN1534254)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 931-980
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原理
- A Cyclase V/VI Antibody
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特异性
- A Cyclase V/VI Polyclonal Antibody detects endogenous levels of A Cyclase V/VI protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human ADCY5/6. AA range:931-980
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ADCY5/6 (Adenylate Cyclase 5/6 (ADCY5/6))
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背景
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Synonyms: ADCY5, Adenylate cyclase type 5, ATP pyrophosphate-lyase 5, Adenylate cyclase type V, Adenylyl cyclase 5, ADCY6, KIAA0422, Adenylate cyclase type 6, ATP pyrophosphate-lyase 6, Adenylate cyclase type VI, Adenylyl cyclase 6, Ca(2+)-inhibitabl
Background: This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],
Gene Name: ADCY5/ADCY6
Protein Name: Adenylate cyclase type 5/6
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分子量
- 138 kDa
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基因ID
- 111, 112
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OMIM
- 600293
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UniProt
- O95622
抗原
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