MAP3K4 抗体 (AA 1281-1330)
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Quick Overview for MAP3K4 抗体 (AA 1281-1330) (ABIN1534230)
抗原
See all MAP3K4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1281-1330
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原理
- MEK Kinase-4 Antibody
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特异性
- MEK Kinase-4 Polyclonal Antibody detects endogenous levels of MEK Kinase-4 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MAP3K4. AA range:1281-1330
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4) antibody
MAP3K4 适用: 人 IHC, WB 宿主: 兔 Monoclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4) (AA 1-100) antibodyMAP3K4 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4) (AA 1201-1300) antibodyMAP3K4 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4F10 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4) (AA 1201-1300) antibodyMAP3K4 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 6A12 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4) (N-Term) antibodyMAP3K4 适用: 人, 小鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4) (AA 53-145) antibodyMAP3K4 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4) antibodyMAP3K4 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4045 unconjugated Recombinant Antibody
anti-Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4) (AA 1201-1300) antibodyMAP3K4 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5D4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4) (AA 75-125) antibodyMAP3K4 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MAP3K4 (Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4))
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别名
- MAP3K4
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背景
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Synonyms: MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1, Mitogen-activated protein kinase kinase kinase 4, MAP three kinase 1, MAPK/ERK kinase kinase 4, MEK kinase 4, MEKK 4
Background: The central core of each mitogen-activated protein kinase (MAPK) pathway is a conserved cascade of 3 protein kinases: an activated MAPK kinase kinase (MAPKKK) phosphorylates and activates a specific MAPK kinase (MAPKK), which then activates a specific MAPK. While the ERK MAPKs are activated by mitogenic stimulation, the CSBP2 and JNK MAPKs are activated by environmental stresses such as osmotic shock, UV irradiation, wound stress, and inflammatory factors.This gene encodes a MAPKKK, the MEKK4 protein, also called MTK1. This protein contains a protein kinase catalytic domain at the C terminus. The N-terminal nonkinase domain may contain a regulatory domain. Expression of MEKK4 in mammalian cells activated the CSBP2 and JNK MAPK pathways, but not the ERK pathway. In vitro kinase studies indicated that recombinant MEKK4 can specifically phosphorylate and activate PRKMK6
Gene Name: MAP3K4
Protein Name: Mitogen-activated protein kinase kinase kinase 4
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分子量
- 181 kDa
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基因ID
- 4216
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OMIM
- 602425
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UniProt
- Q9Y6R4
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途径
- MAPK Pathway
抗原
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