IKZF3 抗体 (AA 361-410)
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Quick Overview for IKZF3 抗体 (AA 361-410) (ABIN1534187)
抗原
See all IKZF3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 361-410
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原理
- Ikaros 3 Antibody
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特异性
- Ikaros 3 Polyclonal Antibody detects endogenous levels of Ikaros 3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human IKZF3. AA range:361-410
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
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别名
- IKZF3
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背景
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Synonyms: IKZF3, ZNFN1A3, Zinc finger protein Aiolos, Ikaros family zinc finger protein 3
Background: This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012],
Gene Name: IKZF3
Protein Name: Zinc finger protein Aiolos
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分子量
- 57 kDa
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基因ID
- 22806
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OMIM
- 606221
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UniProt
- Q9UKT9
抗原
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