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BLZF1 抗体 (AA 10-59)

The 兔 多克隆 anti-BLZF1 antibody (ABIN1534121) specifically detects BLZF1 in WB, ELISA, IHC 和 IF. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN1534121
发货至: 中国
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Quick Overview for BLZF1 抗体 (AA 10-59) (ABIN1534121)

抗原

See all BLZF1 抗体
BLZF1 (Basic Leucine Zipper Nuclear Factor 1 (BLZF1))

适用

  • 42
  • 21
  • 14
  • 5
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  • 3
  • 3
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  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 38
  • 4
兔

克隆类型

  • 40
  • 2
多克隆

标记

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  • 3
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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
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This BLZF1 antibody is un-conjugated

应用范围

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  • 20
  • 14
  • 10
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 10-59

    原理

    Golgin 45 Antibody

    特异性

    Golgin 45 Polyclonal Antibody detects endogenous levels of Golgin 45 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human BLZF1. AA range:10-59

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    BLZF1 (Basic Leucine Zipper Nuclear Factor 1 (BLZF1))

    别名

    BLZF1

    背景

    Synonyms: BLZF1, JEM1, Golgin-45, Basic leucine zipper nuclear factor 1, JEM-1, p45 basic leucine-zipper nuclear factor

    Background: caution:Because of the presence of a potential basic motif and leucine-zipper domain, PubMed:9129147 and PubMed:11056056 have thought that BLZF1 is a potential transcription factor. They found it localized in the nucleus, except isoform 2, which was cytoplasmic. However, homology at several typical position for basic or hydrophobic residues is missing.,function:Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface.,induction:Up-regulated by retinoids.,subunit:Interacts with GORASP2 and with the GTP-bound form of RAB2, but not with other Golgi Rab proteins. GORASP2 and BLZF1 form a RAB2 effector complex on medial Golgi.,tissue specificity:Ubiquitous. Also found in cell lines derived from several hematopoietic pathologies, such as T-cell leukemia, pro-B, pre-B, myeloma, and plasmacytoma cell lines, but not in Burkitt lymphoma cells.,

    Gene Name: BLZF1

    Protein Name: Golgin-45

    分子量

    44 kDa

    基因ID

    8548

    OMIM

    608692

    UniProt

    Q9H2G9
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