ATF6B 抗体 (AA 401-450)
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北京 101111
Quick Overview for ATF6B 抗体 (AA 401-450) (ABIN1534086)
抗原
See all ATF6B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 401-450
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原理
- ATF-6β Antibody
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特异性
- ATF-6β Polyclonal Antibody detects endogenous levels of ATF-6β protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human ATF6B. AA range:401-450
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ATF6B (Activating Transcription Factor 6 beta (ATF6B))
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别名
- ATF6B
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背景
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Synonyms: ATF6B, CREBL1, G13, Cyclic AMP-dependent transcription factor ATF-6 beta, cAMP-dependent transcription factor ATF-6 beta, Activating transcription factor 6 beta, ATF6-beta, Protein G13, cAMP response element-binding protein-related protein,
Background: The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],
Gene Name: ATF6B
Protein Name: Cyclic AMP-dependent transcription factor ATF-6 beta
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分子量
- 76 kDa
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基因ID
- 1388
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OMIM
- 600984
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UniProt
- Q99941
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途径
- Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction
抗原
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