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PHKB 抗体 (AA 661-710)

The 兔 多克隆 anti-PHKB antibody (ABIN1534055) specifically detects PHKB in WB 和 IHC. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN1534055
发货至: 中国
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Quick Overview for PHKB 抗体 (AA 661-710) (ABIN1534055)

抗原

See all PHKB 抗体
PHKB (Phosphorylase Kinase, beta (PHKB))

适用

  • 33
  • 6
  • 2
  • 2
人, 小鼠

宿主

  • 30
  • 3
  • 2
兔

克隆类型

  • 33
  • 2
多克隆

标记

  • 14
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PHKB antibody is un-conjugated

应用范围

  • 26
  • 13
  • 13
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 661-710

    原理

    PHKB Antibody

    特异性

    PHKB Polyclonal Antibody detects endogenous levels of PHKB protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human KPBB. AA range:661-710

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    PHKB (Phosphorylase Kinase, beta (PHKB))

    背景

    Synonyms: PHKB, Phosphorylase b kinase regulatory subunit beta, Phosphorylase kinase subunit beta

    Background: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency

    Gene Name: PHKB

    Protein Name: Phosphorylase b kinase regulatory subunit beta

    分子量

    124 kDa

    基因ID

    5257

    OMIM

    172490

    UniProt

    Q93100

    途径

    Cellular Glucan Metabolic Process
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