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Histone H2B 抗体 (AA 1-50)

The 兔 多克隆 anti-Histone H2B antibody is suitable to detect Histone H2B in samples from 人 和 小鼠. It has been validated for WB, ELISA, IF, ICC 和 IHC (p).
产品编号 ABIN1534054
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Histone H2B 抗体 (AA 1-50) (ABIN1534054)

抗原

See all Histone H2B 抗体
Histone H2B

适用

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人, 小鼠

宿主

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兔

克隆类型

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多克隆

标记

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This Histone H2B antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    AA 1-50

    原理

    Histone H2B Antibody

    特异性

    Histone H2B Polyclonal Antibody detects endogenous levels of Histone H2B protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Histone H2B. AA range:1-50

    亚型

    IgG
  • 应用备注

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Histone H2B

    背景

    Synonyms: HIST1H2BH, H2BFJ, Histone H2B type 1-H, Histone H2B.j, H2B/j

    Background: folate hydrolase 1(FOLH1) Homo sapiens This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alter

    Gene Name: HIST1H2BH

    Protein Name: Histone H2B type 1-H

    分子量

    13 kDa

    OMIM

    602806

    UniProt

    Q93079
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