DOK4 抗体 (AA 11-60)
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Quick Overview for DOK4 抗体 (AA 11-60) (ABIN1534026)
抗原
See all DOK4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 11-60
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原理
- Dok-4 Antibody
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特异性
- Dok-4 Polyclonal Antibody detects endogenous levels of Dok-4 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human DOK4. AA range:11-60
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亚型
- IgG
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anti-Docking Protein 4 (DOK4) (AA 240-326) antibody
DOK4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 4 (DOK4) (AA 228-258), (C-Term) antibodyDOK4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1779-1780 unconjugated
anti-Docking Protein 4 (DOK4) (N-Term) antibodyDOK4 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 4 (DOK4) antibodyDOK4 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 4 (DOK4) (AA 38-87) antibodyDOK4 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig, 猴, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 4 (DOK4) (C-Term) antibodyDOK4 适用: 人, 大鼠, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 4 (DOK4) (N-Term) antibodyDOK4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 4 (DOK4) (N-Term) antibodyDOK4 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 4 (DOK4) (N-Term) antibodyDOK4 适用: 人 WB 宿主: 小鼠 Monoclonal AFfirm9311 unconjugated
anti-Docking Protein 4 (DOK4) (AA 11-60) antibodyDOK4 适用: 人, 小鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- DOK4 (Docking Protein 4 (DOK4))
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别名
- DOK4
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背景
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Synonyms: DOK4, Docking protein 4, Downstream of tyrosine kinase 4, Insulin receptor substrate 5, IRS-5, IRS5
Background: domain:PTB domain mediates receptor interaction.,function:DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.,PTM:Phosphorylated on tyrosine residues in response to insulin, IGF1 or RET stimulation.,similarity:Belongs to the DOK family. Type B subfamily.,similarity:Contains 1 IRS-type PTB domain.,similarity:Contains 1 PH domain.,subunit:Interacts with RET and TEK/TIE2. Interaction with RET is mediated through the PTB domain and requires phosphorylation of RET 'Tyr-1062'.,tissue specificity:Widely expressed. High expression in skeletal muscle, heart, kidney and liver. Weaker expression in spleen, lung and small intestine, brain, heart and. Expressed in both resting and activated peripheral blood T-cells.,
Gene Name: DOK4
Protein Name: Docking protein 4
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分子量
- 37 kDa
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基因ID
- 55715
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OMIM
- 608333
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UniProt
- Q8TEW6
抗原
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