BRSK1 抗体 (AA 361-410)
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北京 101111
Quick Overview for BRSK1 抗体 (AA 361-410) (ABIN1534022)
抗原
See all BRSK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 361-410
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原理
- BRSK1 Antibody
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特异性
- BRSK1 Polyclonal Antibody detects endogenous levels of BRSK1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human BRSK1. AA range:361-410
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亚型
- IgG
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anti-BR Serine/threonine Kinase 1 (BRSK1) (AA 269-321) antibody
BRSK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-BR Serine/threonine Kinase 1 (BRSK1) (AA 310-510) antibodyBRSK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-BR Serine/threonine Kinase 1 (BRSK1) (AA 426-591) antibodyBRSK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BR Serine/threonine Kinase 1 (BRSK1) (AA 355-384) antibodyBRSK1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB40234 unconjugated
anti-BR Serine/threonine Kinase 1 (BRSK1) (AA 654-684), (C-Term) antibodyBRSK1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5415 unconjugated
anti-BR Serine/threonine Kinase 1 (BRSK1) (Internal Region) antibodyBRSK1 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- BRSK1 (BR Serine/threonine Kinase 1 (BRSK1))
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别名
- BRSK1
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背景
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Synonyms: BRSK1, KIAA1811, SAD1, SADB, Serine/threonine-protein kinase BRSK1, Brain-selective kinase 1, Brain-specific serine/threonine-protein kinase 1, BR serine/threonine-protein kinase 1, Serine/threonine-protein kinase SAD-B, Synapses of Amphids
Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-205 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins (By similarity). May be involved in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. Phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UBA domain.,subcellular location:Nuclear in the absence of DNA damage. Translocated to the nucleus in response to UV- or MMS-induced DNA damage.,tissue specificity:Widely expressed, with highest levels in brain and testis. Protein levels remain constant throughout the cell cycle.,
Gene Name: BRSK1
Protein Name: Serine/threonine-protein kinase BRSK1
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分子量
- 86 kDa
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基因ID
- 84446
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OMIM
- 609235
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UniProt
- Q8TDC3
抗原
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