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STEAP2 抗体 (AA 431-480)

The 兔 多克隆 anti-STEAP2 antibody is suitable to detect STEAP2 in samples from 人 和 小鼠. It has been validated for IHC, ELISA, WB 和 IF.
产品编号 ABIN1534012
发货至: 中国
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Quick Overview for STEAP2 抗体 (AA 431-480) (ABIN1534012)

抗原

See all STEAP2 抗体
STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

适用

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人, 小鼠

宿主

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兔

克隆类型

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多克隆

标记

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This STEAP2 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 431-480

    原理

    STEAP2 Antibody

    特异性

    STEAP2 Polyclonal Antibody detects endogenous levels of STEAP2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human STEA2. AA range:431-480

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

    背景

    Synonyms: STEAP2, PCANAP1, STAMP1, Metalloreductase STEAP2, Prostate cancer-associated protein 1, Protein up-regulated in metastatic prostate cancer, PUMPCn, Six-transmembrane epithelial antigen of prostate 2, SixTransMembrane protein of prostate 1

    Background: STEAP2 metalloreductase(STEAP2) Homo sapiens This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

    Gene Name: STEAP2

    Protein Name: Metalloreductase STEAP2

    分子量

    55 kDa

    基因ID

    261729

    OMIM

    605094

    UniProt

    Q8NFT2

    途径

    Transition Metal Ion Homeostasis
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