STEAP2 抗体 (AA 431-480)
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Quick Overview for STEAP2 抗体 (AA 431-480) (ABIN1534012)
抗原
See all STEAP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 431-480
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原理
- STEAP2 Antibody
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特异性
- STEAP2 Polyclonal Antibody detects endogenous levels of STEAP2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human STEA2. AA range:431-480
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))
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背景
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Synonyms: STEAP2, PCANAP1, STAMP1, Metalloreductase STEAP2, Prostate cancer-associated protein 1, Protein up-regulated in metastatic prostate cancer, PUMPCn, Six-transmembrane epithelial antigen of prostate 2, SixTransMembrane protein of prostate 1
Background: STEAP2 metalloreductase(STEAP2) Homo sapiens This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
Gene Name: STEAP2
Protein Name: Metalloreductase STEAP2
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分子量
- 55 kDa
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基因ID
- 261729
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OMIM
- 605094
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UniProt
- Q8NFT2
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途径
- Transition Metal Ion Homeostasis
抗原
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