ZFHX3 抗体 (AA 761-810)
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Quick Overview for ZFHX3 抗体 (AA 761-810) (ABIN1533928)
抗原
See all ZFHX3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 761-810
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原理
- ATBF1 Antibody
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特异性
- ATBF1 Polyclonal Antibody detects endogenous levels of ATBF1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human ZFHX3. AA range:761-810
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ZFHX3 (Zinc Finger Homeobox 3 (ZFHX3))
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别名
- ZFHX3
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背景
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Synonyms: ZFHX3, ATBF1, Zinc finger homeobox protein 3, AT motif-binding factor, AT-binding transcription factor 1, Alpha-fetoprotein enhancer-binding protein, Zinc finger homeodomain protein 3, ZFH-3
Background: This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively regulate c-Myb, and transactivate the cell cycle inhibitor cyclin-dependent kinase inhibitor 1A (also known as p21CIP1). This gene is reported to function as a tumor suppressor in several cancers, and sequence variants of this gene are also associated with atrial fibrillation. Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],
Gene Name: ZFHX3
Protein Name: Zinc finger homeobox protein 3
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分子量
- 404 kDa
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基因ID
- 463
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OMIM
- 104155
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UniProt
- Q15911
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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