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ZFHX3 抗体 (AA 301-400)

ZFHX3 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387456
发货至: 中国
  • 抗原 See all ZFHX3 抗体
    ZFHX3 (Zinc Finger Homeobox 3 (ZFHX3))
    抗原表位
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-400
    适用
    • 15
    • 15
    • 10
    大鼠
    宿主
    • 26
    • 2
    • 1
    克隆类型
    • 28
    • 1
    多克隆
    标记
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZFHX3 antibody is un-conjugated
    应用范围
    • 12
    • 12
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    交叉反应
    大鼠
    预测反应
    Human,Mouse,Dog,Cow,Sheep,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human ATBF1
    亚型
    IgG
    Top Product
    Discover our top product ZFHX3 Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    ZFHX3 (Zinc Finger Homeobox 3 (ZFHX3))
    别名
    ATBF1 (ZFHX3 产品)
    别名
    ZFHX3 antibody, ATBF1 antibody, ATBT antibody, ZNF927 antibody, A230102L03Rik antibody, Atbf1 antibody, WBP9 antibody, mKIAA4228 antibody, RGD1560268 antibody, zax-2 antibody, zinc finger homeobox 3 antibody, AT-binding transcription factor1 antibody, zfhx3 antibody, ZFHX3 antibody, ATBF1/ZFHX4b antibody, Zfhx3 antibody
    背景

    Synonyms: Alpha fetoprotein enhancer binding protein, AT binding transcription factor 1, AT mot binding factor, ATBT, ZFHX3, ZFHX3_HUMAN.

    Background: AT-motif binding factor 1 (ATBF1) binds to the AT-rich core sequence element in the human a-fetoprotein enhancer (1). Alternative splicing generates the ATBF1-A and ATBF1-B (2,3). While ATBF1-A contains a 920-amino acid extension at the N-terminus, both ATBF1-A and ATBF1-B contain 4 DNA-binding homeobox domains (2,3). Additionally, ATBF1-A contains 23 zinc finger motifs while ATBF1-B contains 18 zinc finger motifs (13). The N-terminal extension unique to ATBF1-A has transcriptional repressor activity (4). In the small intestine, ATBF1-A inhibits expression of the brushborder enzyme aminopeptidase-N through direct binding to the AT motif element (5). Besides functioning in transcription regulation, ATBF1 also functions in ATPase activity (6). ATPase activity associated with ATBF1-A is DNA/RNA-dependent and requires both homeobox domains and zinc finger motifs (6). ATBF1 is highly expressed in spleen and brain tissues (7). The gene encoding human ATBF1 maps to chromosome 16q22.3-q23.1 (8).

    途径
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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