PTK6 抗体 (AA 10-59)
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北京 101111
Quick Overview for PTK6 抗体 (AA 10-59) (ABIN1533880)
抗原
See all PTK6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-59
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原理
- Brk Antibody
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特异性
- Brk Polyclonal Antibody detects endogenous levels of Brk protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Breast Tumor Kinase. AA range:10-59
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))
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别名
- Breast Tumor Kinase
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背景
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Synonyms: PTK6, BRK, Protein-tyrosine kinase 6, Breast tumor kinase, Tyrosine-protein kinase BRK
Background: protein tyrosine kinase 6(PTK6) Homo sapiens The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012],
Gene Name: PTK6
Protein Name: Protein-tyrosine kinase 6
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分子量
- 51 kDa
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基因ID
- 5753
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OMIM
- 602004
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UniProt
- Q13882
抗原
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