SMAD4 抗体 (AA 21-70)
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北京 101111
Quick Overview for SMAD4 抗体 (AA 21-70) (ABIN1533870)
抗原
See all SMAD4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-70
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原理
- Smad4 Antibody
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特异性
- Smad4 Polyclonal Antibody detects endogenous levels of Smad4 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Smad4. AA range:21-70
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亚型
- IgG
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anti-SMAD Family Member 4 (SMAD4) (N-Term) antibody
SMAD4 适用: 人 WB, IP, CUT&RUN 宿主: 兔 Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 1-552) antibodySMAD4 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3E2 unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 255-284) antibodySMAD4 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal RB14714 unconjugated
anti-SMAD Family Member 4 (SMAD4) antibodySMAD4 适用: 人, 小鼠 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4G1C6 unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 400-428) antibodySMAD4 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 400-428), (C-Term) antibodySMAD4 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB20720 unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 40-120) antibodySMAD4 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 27-195) antibodySMAD4 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) antibodyKD Validated SMAD4 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB975 unconjugated Recombinant Antibody
anti-SMAD Family Member 4 (SMAD4) (N-Term) antibodySMAD4 适用: 人 WB, IF, IHC (p), IHC (fro) 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SMAD4 (SMAD Family Member 4 (SMAD4))
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别名
- Smad4
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背景
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Synonyms: SMAD4, DPC4, MADH4, Mothers against decapentaplegic homolog 4, MAD homolog 4, Mothers against DPP homolog 4, Deletion target in pancreatic carcinoma 4, SMAD family member 4, SMAD 4, Smad4, hSMAD4
Background: This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, Oct 2009],
Gene Name: SMAD4
Protein Name: Mothers against decapentaplegic homolog 4
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分子量
- 60 kDa
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基因ID
- 4089
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OMIM
- 114500
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UniProt
- Q13485
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途径
- Cell Division Cycle, Chromatin Binding, Autophagy
抗原
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