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TLE4 抗体 (AA 161-210)

The 兔 多克隆 anti-TLE4 antibody (ABIN1533833) specifically detects TLE4 in WB, ELISA, IHC 和 IF. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN1533833
发货至: 中国
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Quick Overview for TLE4 抗体 (AA 161-210) (ABIN1533833)

抗原

See all TLE4 抗体
TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

适用

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人, 大鼠, 小鼠

宿主

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兔

克隆类型

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多克隆

标记

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This TLE4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 161-210

    原理

    TLE4 Antibody

    特异性

    TLE4 Polyclonal Antibody detects endogenous levels of TLE4 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human TLE4. AA range:161-210

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

    别名

    TLE4

    背景

    Synonyms: TLE4, KIAA1261, Transducin-like enhancer protein 4

    Background: caution:Product of a dubious CDS prediction. Found in the 3'UTR of TLE4. No homolog. Large scale identification of a phosphorylated peptide (PubMed:15302935) would require further confirmation.,function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.,similarity:Belongs to the WD repeat Groucho/TLE family.,similarity:Contains 7 WD repeats.,subunit:Homooligomer and heterooligomer with other family members. Binds PAX5, LEF1, TCF7, TCF7L1 and TCF7L2.,tissue specificity:In all tissues examined, mostly in brain, and muscle.,

    Gene Name: TLE4

    Protein Name: Transducin-like enhancer protein 4

    分子量

    83 kDa

    基因ID

    7091

    OMIM

    605132

    UniProt

    Q04727

    途径

    WNT signaling
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