TLE2 抗体 (AA 211-260)
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北京 101111
Quick Overview for TLE2 抗体 (AA 211-260) (ABIN1533832)
抗原
See all TLE2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 211-260
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原理
- TLE2 Antibody
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特异性
- TLE2 Polyclonal Antibody detects endogenous levels of TLE2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human TLE2. AA range:211-260
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))
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别名
- TLE2
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背景
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Synonyms: TLE2, Transducin-like enhancer protein 2, Enhancer of split groucho-like protein 2, ESG2
Background: function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.,similarity:Belongs to the WD repeat Groucho/TLE family.,similarity:Contains 6 WD repeats.,subunit:Homooligomer and heterooligomer with other family members. Binds LEF1, TCF7, TCF7L1, TCF7L2, UTY, HES1 and HES5.,tissue specificity:In all tissues examined, mostly in heart, brain, and muscle.,
Gene Name: TLE2
Protein Name: Transducin-like enhancer protein 2
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分子量
- 79 kDa
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基因ID
- 7089
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OMIM
- 601041
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UniProt
- Q04725
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途径
- WNT signaling
抗原
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