JAK1 抗体 (AA 91-140)
Our Local Distributor
北京 101111
Quick Overview for JAK1 抗体 (AA 91-140) (ABIN1533664)
抗原
See all JAK1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 91-140
-
原理
- JAK1 Antibody
-
特异性
- JAK1 Polyclonal Antibody detects endogenous levels of JAK1 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human JAK1. AA range:91-140
-
亚型
- IgG
-
-
anti-Janus Kinase 1 (JAK1) (pTyr1022) antibody
JAK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 1 (JAK1) (pTyr1022) antibodyJAK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 1 (JAK1) antibodyKD Validated JAK1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2245 unconjugated Recombinant Antibody
anti-Janus Kinase 1 (JAK1) (AA 172-204), (N-Term) antibodyJAK1 适用: 人 WB 宿主: 兔 Polyclonal RB43809 unconjugated
anti-Janus Kinase 1 (JAK1) (AA 866-899), (C-Term) antibodyJAK1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB43812 unconjugated
anti-Janus Kinase 1 (JAK1) (pTyr1022), (pTyr1034) antibodyJAK1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 1 (JAK1) antibodyJAK1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Janus Kinase 1 (JAK1) antibodyJAK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 1 (JAK1) (Ser639) antibodyJAK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- JAK1 (Janus Kinase 1 (JAK1))
-
别名
- JAK1
-
背景
-
Synonyms: JAK1, JAK1A, JAK1B, Tyrosine-protein kinase JAK1, Janus kinase 1, JAK-1
Background: mitogen-activated protein kinase 14(MAPK14) Homo sapiens The protein encoded byThis gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding d
Gene Name: JAK1
Protein Name: Tyrosine-protein kinase JAK1
-
分子量
- 131 kDa
-
OMIM
- 147795
-
UniProt
- P23458
-
途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
抗原
-
