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H2AFX 抗体 (AA 94-143)

The 兔 多克隆 anti-H2AFX antibody (ABIN1533626) specifically detects H2AFX in WB, IF, ELISA, ICC 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1533626
发货至: 中国
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Quick Overview for H2AFX 抗体 (AA 94-143) (ABIN1533626)

抗原

See all H2AFX 抗体
H2AFX (H2A Histone Family, Member X (H2AFX))

适用

  • 220
  • 104
  • 90
  • 14
  • 12
  • 12
  • 11
  • 8
  • 6
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 194
  • 25
  • 2
  • 2
兔

克隆类型

  • 133
  • 90
多克隆

标记

  • 128
  • 11
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 4
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This H2AFX antibody is un-conjugated

应用范围

  • 191
  • 102
  • 83
  • 50
  • 47
  • 37
  • 34
  • 30
  • 17
  • 17
  • 11
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 42
    • 22
    • 18
    • 12
    • 10
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 94-143

    原理

    Histone H2A.X Antibody

    特异性

    Histone H2A.X Polyclonal Antibody detects endogenous levels of Histone H2A.X protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Histone H2AX . AA range:94-143

    亚型

    IgG
  • 应用备注

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    H2AFX (H2A Histone Family, Member X (H2AFX))

    别名

    Histone H2AX

    背景

    Synonyms: H2AFX, H2AX, Histone H2A.x, H2a/x

    Background: thyroglobulin(TG) Homo sapiens Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009],

    Gene Name: H2AFX

    Protein Name: Histone H2A.x

    分子量

    15 kDa

    OMIM

    601772

    UniProt

    P16104

    途径

    Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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