UNG 抗体 (AA 191-240)
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北京 101111
Quick Overview for UNG 抗体 (AA 191-240) (ABIN1533614)
抗原
See all UNG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 191-240
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原理
- UDG Antibody
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特异性
- UDG Polyclonal Antibody detects endogenous levels of UDG protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human UNG. AA range:191-240
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- UNG (Uracil-DNA Glycosylase (UNG))
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别名
- UNG
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背景
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Synonyms: UNG, DGU, UNG1, UNG15, Uracil-DNA glycosylase, UDG
Background: This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010],
Gene Name: UNG
Protein Name: Uracil-DNA glycosylase
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分子量
- 34 kDa
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基因ID
- 7374
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OMIM
- 191525
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UniProt
- P13051
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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