BAF53A 抗体 (AA 201-250)
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北京 101111
Quick Overview for BAF53A 抗体 (AA 201-250) (ABIN1533577)
抗原
See all BAF53A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-250
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原理
- BAF53 Antibody
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特异性
- BAF53 Polyclonal Antibody detects endogenous levels of BAF53 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human ACTL6A. AA range:201-250
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- BAF53A (Actin-Like 6A (BAF53A))
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别名
- ACTL6A
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背景
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Synonyms: ACTL6A, BAF53, BAF53A, INO80K, Actin-like protein 6A, 53 kDa BRG1-associated factor A, Actin-related protein Baf53a, ArpNbeta, BRG1-associated factor 53A, BAF53A, INO80 complex subunit K
Background: This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling.This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila, the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein
Gene Name: ACTL6A
Protein Name: Actin-like protein 6A
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分子量
- 47 kDa
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基因ID
- 86
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OMIM
- 604958
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UniProt
- O96019
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途径
- Chromatin Binding, Photoperiodism
抗原
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