MYST2 抗体 (AA 131-180)
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Quick Overview for MYST2 抗体 (AA 131-180) (ABIN1533558)
抗原
See all MYST2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 131-180
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原理
- HBO1 Antibody
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特异性
- HBO1 Polyclonal Antibody detects endogenous levels of HBO1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MYST2. AA range:131-180
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亚型
- IgG
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anti-MYST Histone Acetyltransferase 2 (MYST2) (AA 55-193) antibody
MYST2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MYST Histone Acetyltransferase 2 (MYST2) (AA 1-200) antibodyMYST2 适用: 人, 小鼠, 猴 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1D9H9 unconjugated
anti-MYST Histone Acetyltransferase 2 (MYST2) (Internal Region) antibodyMYST2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MYST Histone Acetyltransferase 2 (MYST2) antibodyKD Validated MYST2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2390 unconjugated Recombinant Antibody
anti-MYST Histone Acetyltransferase 2 (MYST2) (Internal Region) antibodyMYST2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MYST Histone Acetyltransferase 2 (MYST2) (AA 512-611) antibodyMYST2 适用: 人 WB, RNAi 宿主: 小鼠 Monoclonal 2G5 unconjugated
anti-MYST Histone Acetyltransferase 2 (MYST2) (AA 1-214) antibodyMYST2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MYST Histone Acetyltransferase 2 (MYST2) (Internal Region) antibodyMYST2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-MYST Histone Acetyltransferase 2 (MYST2) (AA 1-611) antibodyMYST2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-MYST Histone Acetyltransferase 2 (MYST2) (AA 1-611) antibodyMYST2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MYST2 (MYST Histone Acetyltransferase 2 (MYST2))
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别名
- MYST2
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背景
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Synonyms: KAT7, HBO1, HBOa, MYST2, Histone acetyltransferase KAT7, Histone acetyltransferase binding to ORC1, Lysine acetyltransferase 7, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2, MYST-2
Background: catalytic activity:Acetyl-CoA + histone = CoA + acetylhistone.,domain:The C2HC-type zinc finger is required for interaction with MCM2 and ORC1L.,domain:The N-terminus is involved in transcriptional repression, while the C-terminus mediates AR-interaction.,function:Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the MYST (SAS/MOZ) family.,similarity:Contains 1 C2HC-type zinc finger.,subunit:Component of the HBO1 complex composed at least of ING4 or ING5, MYTS2/HBO1, EAF6, and one of PHF15, PHF16 and PHF17. Interacts with MCM2 and ORC1L. Interacts with the androgen receptor (AR) in the presence of dihydrotestosterone.,tissue specificity:Ubiquitously expressed, with highest levels in testis.,
Gene Name: KAT7
Protein Name: Histone acetyltransferase KAT7
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分子量
- 70 kDa
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基因ID
- 11143
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OMIM
- 609880
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UniProt
- O95251
抗原
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