FARP2 抗体 (AA 331-380)
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北京 101111
Quick Overview for FARP2 抗体 (AA 331-380) (ABIN1533551)
抗原
See all FARP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 331-380
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原理
- FIR Antibody
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特异性
- FIR Polyclonal Antibody detects endogenous levels of FIR protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human FIR. AA range:331-380
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))
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别名
- FIR
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背景
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Synonyms: FARP2, KIAA0793, PLEKHC3, FERM, RhoGEF and pleckstrin domain-containing protein 2, FERM domain including RhoGEF, FIR, Pleckstrin homology domain-containing family C member 3, PH domain-containing family C member 3
Background: function:Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 FERM domain.,similarity:Contains 2 PH domains.,subunit:Interacts with PLXNA1. Interaction with PLXNA1 or PIP5K1C lowers its guanine nucleotide exchange activity. Dissociates from PLXNA1 when SEMA3A binds to the receptor. Interacts with PIP5K1C via its FERM domain. The interaction with PIP5K1C is enhanced by SEMA3A binding.,
Gene Name: FARP2
Protein Name: FERM RhoGEF and pleckstrin domain-containing protein 2
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分子量
- 119 kDa
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基因ID
- 9855
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UniProt
- O94887
抗原
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