AIRE 抗体 (AA 91-140)
Our Local Distributor
北京 101111
Quick Overview for AIRE 抗体 (AA 91-140) (ABIN1533513)
抗原
See all AIRE 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 91-140
-
原理
- AIRE-1 Antibody
-
特异性
- AIRE-1 Polyclonal Antibody detects endogenous levels of AIRE-1 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human AIRE. AA range:91-140
-
亚型
- IgG
-
-
anti-Autoimmune Regulator (AIRE) (C-Term) antibody
Verified AIRE 适用: 人 WB, ELISA, IF, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (AA 30-130) antibodyAIRE 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (Internal Region) antibodyVerified AIRE 适用: 人, Pig WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (N-Term) antibodyAIRE 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (AA 64-92) antibodyAIRE 适用: 人 WB, IF 宿主: 兔 Polyclonal RB30050 unconjugated
anti-Autoimmune Regulator (AIRE) (AA 39-108) antibodyAIRE 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (pSer156) antibodyAIRE 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (Internal Region) antibodyVerified AIRE 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (N-Term) antibodyAIRE 适用: 人, 小鼠, 大鼠, 犬, 马, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Autoimmune Regulator (AIRE) (AA 218-267) antibodyAIRE 适用: 人, 马, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- AIRE (Autoimmune Regulator (AIRE))
-
别名
- AIRE
-
背景
-
Synonyms: AIRE, APECED, Autoimmune regulator, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, APECED protein
Background: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012],
Gene Name: AIRE
Protein Name: Autoimmune regulator
-
分子量
- 57 kDa
-
基因ID
- 326
-
OMIM
- 109100
-
UniProt
- O43918
-
途径
- Chromatin Binding
抗原
-
