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Sodium Channel 抗体 (AA 1466-1515)

The 兔 多克隆 anti-Sodium Channel antibody (ABIN484020) specifically detects Sodium Channel in IHC, ELISA, WB 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN484020
发货至: 中国
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Quick Overview for Sodium Channel 抗体 (AA 1466-1515) (ABIN484020)

抗原

Sodium Channel

适用

人, 小鼠, 大鼠

宿主

  • 2
兔

克隆类型

  • 2
多克隆

标记

  • 2
This Sodium Channel antibody is un-conjugated

应用范围

Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 1
    • 1
    • 1
    AA 1466-1515

    原理

    Na+ CP-pan Antibody

    特异性

    Na+ CP-pan Polyclonal Antibody detects endogenous levels of Na+ CP-pan protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Sodium Channel. AA range:1466-1515

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Sodium Channel

    背景

    Synonyms: SCN1A; NAC1; SCN1; Sodium channel protein type 1 subunit alpha; Sodium channel protein brain I subunit alpha; Sodium channel protein type I subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.1; SCN2A; NAC2; SCN2A1; SCN2A2; Sodiu

    Background: Voltage-dependent sodium channels are heteromeric complexes that regulate sodium exchange between intracellular and extracellular spaces and are essential for the generation and propagation of action potentials in muscle cells and neurons. Each sodium channel is composed of a large pore-forming, glycosylated alpha subunit and two smaller beta subunits.This gene encodes a sodium channel alpha subunit, which has four homologous domains, each of which contains six transmembrane regions. Allelic variants of this gene are associated with generalized epilepsy with febrile seizures and epileptic encephalopathy. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, th

    Gene Name: SCN1A/SCN2A/SCN3A/SCN4A/SCN5A/SCN8A/SCN9A/SCN10A/SCN11A

    Protein Name: Sodium channel protein type 1 subunit alpha

    分子量

    227 kDa

    基因ID

    6323, 6326, 6328

    OMIM

    182389

    UniProt

    P35498
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