Retinoic Acid Receptor beta 抗体 (AA 331-380)
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Quick Overview for Retinoic Acid Receptor beta 抗体 (AA 331-380) (ABIN484010)
抗原
See all Retinoic Acid Receptor beta (RARB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 331-380
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原理
- RARβ Antibody
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特异性
- RARβ Polyclonal Antibody detects endogenous levels of RARβ protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Retinoic Acid Receptor beta. AA range:331-380
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))
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别名
- Retinoic Acid Receptor beta
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背景
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Synonyms: RARB, HAP, NR1B2, Retinoic acid receptor beta, RAR-beta, HBV-activated protein, Nuclear receptor subfamily 1 group B member 2, RAR-epsilon
Background: This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants. [provided by RefSeq, Mar 2014],
Gene Name: RARB
Protein Name: Retinoic acid receptor beta
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分子量
- 50 kDa
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基因ID
- 5915
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OMIM
- 180220
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UniProt
- P10826
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途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
抗原
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