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Dynamitin 抗体 (AA 341-390)

This 兔 多克隆 antibody specifically detects Dynamitin in WB, ELISA, IHC 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1533369
发货至: 中国
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Quick Overview for Dynamitin 抗体 (AA 341-390) (ABIN1533369)

抗原

See all Dynamitin (DCTN2) 抗体
Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

适用

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人, 小鼠, 大鼠

宿主

  • 53
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兔

克隆类型

  • 55
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多克隆

标记

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This Dynamitin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 6
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    AA 341-390

    原理

    Dynactin 2 Antibody

    特异性

    Dynactin 2 Polyclonal Antibody detects endogenous levels of Dynactin 2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human p50 Dynamitin. AA range:341-390

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

    别名

    p50 Dynamitin

    背景

    Synonyms: DCTN2, DCTN50, Dynactin subunit 2, 50 kDa dynein-associated polypeptide, Dynactin complex 50 kDa subunit, DCTN-50, p50 dynamitin

    Background: This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2012],

    Gene Name: DCTN2

    Protein Name: Dynactin subunit 2

    分子量

    44 kDa

    基因ID

    10540

    OMIM

    138972

    UniProt

    Q13561

    途径

    M Phase, Ribonucleoprotein Complex Subunit Organization
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