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MMP2 抗体 (AA 611-660)

This 兔 多克隆 antibody specifically detects MMP2 in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 人, 大鼠, 小鼠 和 猴.It has been mentioned in 1 publication
产品编号 ABIN1533350
发货至: 中国
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Quick Overview for MMP2 抗体 (AA 611-660) (ABIN1533350)

抗原

See all MMP2 抗体
MMP2 (Matrix Metalloproteinase 2 (MMP2))

适用

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人, 大鼠, 小鼠, 猴

宿主

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兔

克隆类型

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  • 85
多克隆

标记

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This MMP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 611-660

    原理

    MMP-2 Antibody

    特异性

    MMP-2 Polyclonal Antibody detects endogenous levels of MMP-2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human MMP-2. AA range:611-660

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • Matsumoto, Niimi, Kohyama: "Characterization of fibrosis-promoting factors and siRNA-mediated therapies in C-protein-induced experimental autoimmune myocarditis." in: Cellular immunology, Vol. 279, Issue 1, pp. 70-7, (2012) (PubMed).

  • 抗原

    MMP2 (Matrix Metalloproteinase 2 (MMP2))

    别名

    MMP-2

    背景

    Synonyms: MMP2, CLG4A, 72 kDa type IV collagenase, 72 kDa gelatinase, Gelatinase A, Matrix metalloproteinase-2, MMP-2, TBE-1

    Background: matrix metallopeptidase 2(MMP2) Homo sapiens This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction.The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Win

    Gene Name: MMP2

    Protein Name: 72 kDa type IV collagenase

    分子量

    73 kDa

    基因ID

    4313

    OMIM

    120360

    UniProt

    P08253

    途径

    Activation of Innate immune Response
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