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NOS2 抗体 (AA 1101-1150)

The 兔多克隆 anti-NOS2 antibody (ABIN1533331) specifically detects NOS2 in WB, ELISA, ICC, IF 和 IHC (p). The antibody is reactive with 人, 小鼠和大鼠 samples.

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using iNOS Antibody. (NOS2 抗体 (AA 1101-1150))

IHC

Immunofluorescence analysis of HepG2 cells, using iNOS Antibody. (NOS2 抗体 (AA 1101-1150))

3 images

产品编号 ABIN1533331

发货至: 中国

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中国
北京 101111

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Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

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Quick Overview for NOS2 抗体 (AA 1101-1150) (ABIN1533331)

抗原

See all NOS2 抗体

NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This NOS2 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product NOS2 Primary Antibody

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AA 1101-1150

原理

NOS2 Antibody

特异性

NOS2 Polyclonal Antibody detects endogenous levels of NOS2 protein.

纯化方法

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

纯度

> 95 %

免疫原

The antiserum was produced against synthesized peptide derived from human iNOS. AA range:1101-1150

亚型

IgG
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 14-100) antibody
NOS2 适用: 小鼠 WB, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) antibody
NOS2 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 4E5 unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 43-213) antibody
NOS2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 518-694) antibody
NOS2 适用: 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 830-860) antibody
NOS2 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB18210 unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) (Thr177) antibody
NOS2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) antibody
NOS2 适用: 人 WB, ICC, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 533-696) antibody
NOS2 适用: 人 WB 宿主: 小鼠 Monoclonal C6 unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 533-696) antibody
NOS2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) antibody
NOS2 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Monoclonal ARC0832 unconjugated

应用备注

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C/1 year

有效期

12 months
抗原

NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

别名

iNOS

背景

Synonyms: NOS2, NOS2A, Nitric oxide synthase, inducible, Hepatocyte NOS, HEP-NOS, Inducible NO synthase, Inducible NOS, iNOS, NOS type II, Peptidyl-cysteine S-nitrosylase NOS2
Background: function:Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.,induction:Regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation.,miscellaneous:Canine and feline parvoviruses bind human and feline transferrin receptors and use these receptors to enter and infect cells.,miscellaneous:Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemia resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.,PTM:N- and O-glycosylated, phosphorylated and palmitoylated. The serum form is only glycosylated.,PTM:Palmitoylated on both Cys-62 and Cys-67. Cys-62 seems to be the major site of palmitoylation.,PTM:Proteolytically cleaved on Arg-100 to produce the soluble serum form (sTfR).,similarity:Belongs to the peptidase M28 family. M28B subfamily.,similarity:Contains 1 PA (protease associated) domain.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Homodimer, disulfide-linked. Binds one transferrin or HFE molecule per subunit. Binds the HLA class II histocompatibility antigen, DR1. Interacts with SH3BP3. Interacts with Machupo arenavirus GPC.,
Gene Name: NOS2, INOS
Protein Name: Nitric oxide synthase inducible

分子量

131 kDa

OMIM

163730

UniProt

P35228

途径

Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process