GZMB 抗体 (AA 10-59)
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北京 101111
Quick Overview for GZMB 抗体 (AA 10-59) (ABIN1533296)
抗原
See all GZMB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-59
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原理
- Granzyme B/H Antibody
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特异性
- Granzyme B/H Polyclonal Antibody detects endogenous levels of Granzyme B/H protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Granzyme B. AA range:10-59
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GZMB (Granzyme B (GZMB))
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别名
- Granzyme B
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背景
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Synonyms: GZMB, CGL1, CSPB, CTLA1, GRB, Granzyme B, C11, CTLA-1, Cathepsin G-like 1, CTSGL1, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, HLP, SECT, T-cell serine protease 1-3E, GZMH, C
Background: This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016],
Gene Name: GZMB/GZMH
Protein Name: Granzyme B/H
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分子量
- 27 kDa
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基因ID
- 2999
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OMIM
- 123910
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UniProt
- P10144
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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