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GZMB 抗体 (AA 10-59)

This 兔 多克隆 antibody specifically detects GZMB in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1533296
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GZMB 抗体 (AA 10-59) (ABIN1533296)

抗原

See all GZMB 抗体
GZMB (Granzyme B (GZMB))

适用

  • 204
  • 55
  • 47
  • 12
  • 4
  • 4
  • 3
  • 1
人, 小鼠, 大鼠

宿主

  • 126
  • 94
  • 4
兔

克隆类型

  • 121
  • 103
多克隆

标记

  • 110
  • 19
  • 13
  • 7
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GZMB antibody is un-conjugated

应用范围

  • 98
  • 78
  • 58
  • 46
  • 37
  • 28
  • 26
  • 18
  • 16
  • 15
  • 14
  • 9
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 50
    • 28
    • 23
    • 16
    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 10-59

    原理

    Granzyme B/H Antibody

    特异性

    Granzyme B/H Polyclonal Antibody detects endogenous levels of Granzyme B/H protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Granzyme B. AA range:10-59

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    GZMB (Granzyme B (GZMB))

    别名

    Granzyme B

    背景

    Synonyms: GZMB, CGL1, CSPB, CTLA1, GRB, Granzyme B, C11, CTLA-1, Cathepsin G-like 1, CTSGL1, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, HLP, SECT, T-cell serine protease 1-3E, GZMH, C

    Background: This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016],

    Gene Name: GZMB/GZMH

    Protein Name: Granzyme B/H

    分子量

    27 kDa

    基因ID

    2999

    OMIM

    123910

    UniProt

    P10144

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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