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FGFR2 抗体 (AA 471-520)

This 兔 多克隆 antibody specifically detects FGFR2 in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1533272
发货至: 中国
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Room 801-803
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Quick Overview for FGFR2 抗体 (AA 471-520) (ABIN1533272)

抗原

See all FGFR2 抗体
FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

适用

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人, 小鼠, 大鼠

宿主

  • 146
  • 20
  • 10
  • 1
  • 1
兔

克隆类型

  • 126
  • 52
多克隆

标记

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This FGFR2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 471-520

    原理

    FGF Receptor 2 Antibody

    特异性

    Bek Polyclonal Antibody detects endogenous levels of Bek protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human FGFR2. AA range:471-520

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

    别名

    FGFR2

    背景

    Synonyms: FGFR2, BEK, KGFR, KSAM, Fibroblast growth factor receptor 2, FGFR-2, K-sam, KGFR, Keratinocyte growth factor receptor, CD antigen CD332

    Background: The protein encoded byThis gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, C

    Gene Name: FGFR2 BEK KGFR KSAM

    Protein Name: Fibroblast growth factor receptor 2

    分子量

    92 kDa

    基因ID

    2263

    OMIM

    176943

    UniProt

    P21802

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding
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