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Dysferlin 抗体 (AA 1981-2030)

The 兔 多克隆 anti-Dysferlin antibody is suitable to detect Dysferlin in samples from 人 和 小鼠. It has been validated for WB, ELISA 和 IF.
产品编号 ABIN1533258
发货至: 中国
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Quick Overview for Dysferlin 抗体 (AA 1981-2030) (ABIN1533258)

抗原

See all Dysferlin (DYSF) 抗体
Dysferlin (DYSF)

适用

  • 80
  • 45
  • 17
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
人, 小鼠

宿主

  • 74
  • 5
  • 1
兔

克隆类型

  • 55
  • 25
多克隆

标记

  • 28
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Dysferlin antibody is un-conjugated

应用范围

  • 39
  • 33
  • 26
  • 25
  • 23
  • 21
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 16
    • 13
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1981-2030

    原理

    Dysferlin Antibody

    特异性

    Dysferlin Polyclonal Antibody detects endogenous levels of Dysferlin protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Dysferlin. AA range:1981-2030

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Dysferlin (DYSF)

    别名

    Dysferlin

    背景

    Synonyms: DYSF, FER1L1, Dysferlin, Dystrophy-associated fer-1-like protein, Fer-1-like protein 1

    Background: dysferlin(DYSF) Homo sapiens The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition,The protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2008],

    Gene Name: DYSF

    Protein Name: Dysferlin

    分子量

    237 kDa

    基因ID

    8291

    OMIM

    253601

    UniProt

    O75923
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