Cadherin 抗体 (AA 833-882)
Our Local Distributor
北京 101111
Quick Overview for Cadherin 抗体 (AA 833-882) (ABIN1533230)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 833-882
-
原理
- E-cadherin Antibody
-
特异性
- E-cadherin Polyclonal Antibody detects endogenous levels of E-cadherin protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human Cadherin. AA range:833-882
-
亚型
- IgG
-
-
anti-Cadherin (AA 841-882) antibody
适用: 人 WB, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin (AA 739-767), (C-Term) antibody适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- Cadherin
-
背景
-
Synonyms: CDH1, CDHE, UVO, Cadherin-1, CAM 120/80, Epithelial cadherin, E-cadherin, Uvomorulin, CD antigen CD324, CDH2, CDHN, NCAD, Cadherin-2, CDw325, Neural cadherin, N-cadherin, CD antigen CD325, CDH3, CDHP, Cadherin-3, Placental cadherin, P-cadhe
Background: This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015],
Gene Name: CDH1
Protein Name: Cadherin-1
-
分子量
- 97 kDa
-
基因ID
- 999, 1000, 1001
-
OMIM
- 137215
-
UniProt
- P12830
抗原
-
