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Cadherin 抗体 (AA 841-882) (Biotin)

适用: 人, 小鼠 WB, IHC (p), ELISA, IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN687684
发货至: 中国
  • 抗原 See all Cadherin products
    Cadherin
    抗原表位
    • 15
    • 8
    • 2
    • 2
    • 1
    • 1
    AA 841-882
    适用
    • 24
    • 22
    • 7
    • 7
    • 4
    • 3
    • 1
    • 1
    人, 小鼠
    宿主
    • 22
    • 4
    克隆类型
    • 21
    • 5
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cadherin antibody is conjugated to Biotin
    应用范围
    • 23
    • 15
    • 14
    • 13
    • 7
    • 7
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Cow,Pig,Horse,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human E-cadherin
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    Cadherin
    Abstract
    Cadherin 产品
    别名
    ci-cadherin antibody, cadherin antibody, ci-cadherin antibody, LOC430062 antibody
    背景

    Synonyms: UVO, CDHE, ECAD, LCAM, Arc-1, CD324, Cadherin-1, CAM 12/8, Epithelial cadherin, E-cadherin, Uvomorulin, CDH1

    Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.

    基因ID
    999
    UniProt
    P12830
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